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Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant.


ABSTRACT: In 2014, novel highly pathogenic avian influenza A H5N2, H5N5, H5N6, and H5N8 viruses caused outbreaks in Asia, Europe, and North America. The H5 genes of these viruses form a monophyletic group that evolved from a clade 2.3.4 H5N1 variant. This rapid emergence of new H5Nx combinations is unprecedented in the H5N1 evolutionary history.

SUBMITTER: de Vries E 

PROVIDER: S-EPMC4412238 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature

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Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant.

de Vries Erik E   Guo Hongbo H   Dai Meiling M   Rottier Peter J M PJ   van Kuppeveld Frank J M FJ   de Haan Cornelis A M CA  

Emerging infectious diseases 20150501 5


In 2014, novel highly pathogenic avian influenza A H5N2, H5N5, H5N6, and H5N8 viruses caused outbreaks in Asia, Europe, and North America. The H5 genes of these viruses form a monophyletic group that evolved from a clade 2.3.4 H5N1 variant. This rapid emergence of new H5Nx combinations is unprecedented in the H5N1 evolutionary history. ...[more]

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