Prognostic significance of the BAALC gene expression in adult patients with acute myeloid leukemia: A meta-analysis.

ABSTRACT: Numerous studies have investigated the prognostic role of brain and acute leukemia, cytoplasmic (BAALC) gene expression in adult patients with acute myeloid leukemia (AML); however, the results are inconclusive. A meta-analysis was conducted to provide a comprehensive evaluation of the prognostic role of BAALC gene expression in AML. Eligible studies were searched through PubMed, Embase, the Cochrane Library, the China National Knowledge Infrastructure and the China Biology Medicine Disc. Correlations between the BAALC gene expression and clinicopathological features and prognosis were analyzed. A total of 15 studies were examined. The pooled results suggest that high BAALC expression had an unfavorable outcome in AML. The combined hazard ratio (HR) for overall

SUBMITTER: Xiao SJ 

PROVIDER: S-EPMC4486884 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature