Theory of mind impairment in patients with behavioural variant fronto-temporal dementia (bv-FTD) increases caregiver burden.

ABSTRACT:

Background

Theory of mind (ToM), the capacity to infer the intention, beliefs and emotional states of others, is frequently impaired in behavioural variant fronto-temporal dementia patients (bv-FTDp); however, its impact on caregiver burden is unexplored.

Setting

National Institute of Neurological Disorders and Stroke, National Institutes of Health.

Subjects

bv-FTDp (n = 28), a subgroup of their caregivers (n = 20) and healthy controls (n = 32).

Methods

we applied a faux-pas (FP) task as a ToM measure in bv-FTDp and healthy controls and the Zarit Burden Interview as a measure of burden in patients' caregivers. Patients underwent structural MRI; we used voxel-based morphometry to examine relationships between regional atrophy and ToM impairment and caregiver bur

SUBMITTER: Brioschi Guevara A 

PROVIDER: S-EPMC4547924 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature