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Human pain and genetics: some basics.

ABSTRACT: Human pain causes untold misery and suffering, with major impact on functioning and resources. Recent advances in genetics have revealed that subtle changes in DNA could partly explain the variation in individual differences in pain. Various genes encoding for receptors are now known to play a major role in the sensitivity, perception and expression of pain. The fields of epigenetics and proteomics hold promises in the way pain could be treated and managed in future.

SUBMITTER: James S

PROVIDER: S-EPMC4590159 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature

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Human pain and genetics: some basics.

James Sabu S

British journal of pain 20131101 4

Human pain causes untold misery and suffering, with major impact on functioning and resources. Recent advances in genetics have revealed that subtle changes in DNA could partly explain the variation in individual differences in pain. Various genes encoding for receptors are now known to play a major role in the sensitivity, perception and expression of pain. The fields of epigenetics and proteomics hold promises in the way pain could be treated and managed in future. ...[more]

PMID: 26516521

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