Altered Basal Ganglia Network Integration in Schizophrenia.
Ontology highlight
ABSTRACT: Unlabelled
The basal ganglia involve in a range of functions that are disturbed in schizophrenia patients. This study decomposed the resting-state data of 28 schizophrenia patients and 31 healthy controls with spatial independent component analysis and identified increased functional integration in the bilateral caudate nucleus in schizophrenia patients. Further, the caudate nucleus in patients showed altered functional connection with the prefrontal area and cerebellum. These results identified the importance of basal ganglia in schizophrenia patients.Clinical trial registration
Chinese Clinical Trial Registry. Registration number ChiCTR-RCS-14004878.
SUBMITTER: Duan M
PROVIDER: S-EPMC4600918 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Altered Basal Ganglia Network Integration in Schizophrenia.
Duan Mingjun M Chen Xi X He Hui H Jiang Yuchao Y Jiang Sisi S Xie Qiankun Q Lai Yongxiu Y Luo Cheng C Yao Dezhong D
Frontiers in human neuroscience 20151012
<h4>Unlabelled</h4>The basal ganglia involve in a range of functions that are disturbed in schizophrenia patients. This study decomposed the resting-state data of 28 schizophrenia patients and 31 healthy controls with spatial independent component analysis and identified increased functional integration in the bilateral caudate nucleus in schizophrenia patients. Further, the caudate nucleus in patients showed altered functional connection with the prefrontal area and cerebellum. These results id ...[more]
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