Insulin Resistance Is a Risk Factor for Increased Intraocular Pressure: The Hisayama Study.

ABSTRACT:

Purpose

To investigate association of the homeostasis model assessment of insulin resistance (HOMA-IR), a surrogate index of insulin resistance, with IOP in a general Japanese population.

Methods

In 2007, a total of 3119 Japanese community-dwellers, aged 40 years or older, underwent eye examinations, including IOP measurement with a noncontact tonometer. Of these, 2254 residents participated in this study. Fasting serum glucose and plasma insulin were measured to determine the HOMA-IR. The association of HOMA-IR with IOP was assessed using a linear regression model, adjusted for age and possible risk factors that can elevate IOP.

Results

The mean IOP ± SD was 13.7 ± 2.7 mm Hg in the right eye and 13.6 ± 2.7 mm Hg in the left eye. After adjusting for age, sex, systolic

SUBMITTER: Fujiwara K 

PROVIDER: S-EPMC4684191 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature