Occupational exposures and chronic kidney disease: Possible associations with endotoxin and ultrafine particles.

ABSTRACT:

Background

Chronic kidney disease (CKD) carries a high public health burden yet there is limited research on occupational factors, which are examined in this retrospective case-control study.

Methods

Newly diagnosed cases of CKD (n = 547) and controls (n = 508) from North Carolina provided detailed work histories in telephone interviews. Unconditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs).

Results

There was heterogeneity in the association of CKD and agricultural work, with crop production associated with increased risk and work with livestock associated with decreased risk. Work with cutting/cooling/lubricating oils was associated with a reduced risk. CKD risk was increased for working in dusty conditions.

Co

SUBMITTER: Sponholtz TR 

PROVIDER: S-EPMC4715760 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature