Ontology highlight
ABSTRACT:
SUBMITTER: Hu G
PROVIDER: S-EPMC4755006 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Hu Guorui G Fan Yanjie Y Wang Lili L Yao Ru-En RE Huang Xiaodong X Shen Yiping Y Yu Yongguo Y Gu Xuefan X
Molecular cytogenetics 20160216
<h4>Background</h4>Idiopathic short stature (ISS) refers to short stature with no evident etiologies. The custom genome-wide microarray specifically designed to cover height-related genes may be helpful to detect copy number variations (CNVs) in ISS patients, which may be missed by the general microarray. The aim of the study was to validate the applicability of the custom microarray and to analyze CNVs in Chinese ISS children.<h4>Results</h4>Sixty non-polymorphic CNVs were identified in 119 ISS ...[more]