Prevalence of HIV-associated neurocognitive disorders in the Multicenter AIDS Cohort Study.

ABSTRACT:

Objective

To evaluate the frequency of HIV-associated neurocognitive disorder (HAND) in HIV+ individuals and determine whether the frequency of HAND changed over 4 years of follow-up.

Methods

The Multicenter AIDS Cohort Study (MACS) is a prospective study of gay/bisexual men. Beginning in 2007, all MACS participants received a full neuropsychological test battery and functional assessments every 2 years to allow for HAND classification.

Results

The frequency of HAND for the 364 HIV+ individuals seen in 2007-2008 was 33% and for the 197 HIV+ individuals seen at all time periods during the 2007-2008, 2009-2010, and 2011-2012 periods were 25%, 25%, and 31%, respectively. The overall frequency of HAND increased from 2009-2010 to 2011-2012 (p = 0.048). Over the 4-year stud

SUBMITTER: Sacktor N 

PROVIDER: S-EPMC4776086 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature