Glycemic Index, Glycemic Load, and Lung Cancer Risk in Non-Hispanic Whites.

ABSTRACT:

Background

Postprandial glucose (PPG) and insulin responses play a role in carcinogenesis. We evaluated the association between dietary glycemic index (GI) and glycemic load (GL), markers of carbohydrate intake and PPG, and lung cancer risk in non-Hispanic whites.

Methods

GL and GI were assessed among 1,905 newly diagnosed lung cancer cases recruited from the University of Texas MD Anderson Cancer Center (Houston, TX) and 2,413 healthy controls recruited at Kelsey-Seybold Clinics (Houston, TX). We assessed associations between quintiles of GI/GL and lung cancer risk and effect modification by various risk factors. ORs and 95% confidence intervals (CI) were estimated using multivariable logistic regression.

Results

We observed a significant association between GI [5th

SUBMITTER: Melkonian SC 

PROVIDER: S-EPMC4780226 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature