Time to Osteoporosis and Major Fracture in Older Men: The MrOS Study.

ABSTRACT:

Introduction

For older men who undergo bone mineral density (BMD) testing, the optimal osteoporosis screening schedule is unknown. Time-to-disease estimates are necessary to inform screening intervals.

Methods

A prospective cohort study of 5,415 community-dwelling men aged ≥65 years without hip or clinical vertebral fracture or antifracture treatment at baseline was conducted. Participants had concurrent BMD and fracture follow-up between 2000 and 2009, and additional fracture follow-up through 2014. Data were analyzed in 2015. Time to incident osteoporosis (lowest T-score ≤ -2.50) for men without baseline osteoporosis, and time to hip or clinical vertebral fracture or major osteoporotic fracture for men without or with baseline osteoporosis, were estimated.

Results

N

SUBMITTER: Gourlay ML 

PROVIDER: S-EPMC4875888 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature