Importance of hereditary and selected environmental risk factors in the etiology of inflammatory breast cancer: a case-comparison study.

ABSTRACT:

Background

To assess the importance of heredity in the etiology of inflammatory breast cancer (IBC), we compared IBC patients to several carefully chosen comparison groups with respect to the prevalence of first-degree family history of breast cancer.

Methods

IBC cases (n = 141) were compared to non-inflammatory breast cancer cases (n = 178) ascertained through George Washington University (GWU) with respect to the prevalence of first-degree family history of breast cancer and selected environmental/lifestyle risk factors for breast cancer. Similar comparisons were conducted with subjects from three case-control studies: breast cancer cases (n = 1145) and unaffected controls (n = 1142) from the Cancer Genetic Markers of Susceptibility (CGEMS) study, breast cancer cases (n = 

SUBMITTER: Moslehi R 

PROVIDER: S-EPMC4881056 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature