Neonatal seizures triple the risk of a remote seizure after perinatal ischemic stroke.

ABSTRACT:

Objectives

To determine incidence rates and risk factors of remote seizure after perinatal arterial ischemic stroke.

Methods

We retrospectively identified a population-based cohort of children with perinatal arterial ischemic stroke (presenting acutely or in a delayed fashion) from a large Northern Californian integrated health care system. We determined incidence and predictors of a remote seizure (unprovoked seizure after neonatal period, defined as 28 days of life) by survival analyses, and measured epilepsy severity in those with active epilepsy (≥1 remote seizure and maintenance anticonvulsant treatment) at last follow-up.

Results

Among 87 children with perinatal stroke, 40 (46%) had a seizure in the neonatal period. During a median follow-up of 7.1 years (interq

SUBMITTER: Fox CK 

PROVIDER: S-EPMC4898314 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature