Ontology highlight
ABSTRACT:
SUBMITTER: Miyamoto T
PROVIDER: S-EPMC4926141 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Miyamoto Tatsuki T Yokota Akiko A Tsuneda Satoshi S Noda Naohiro N
Toxins 20160604 6
Nitrosomonas europaea carries numerous toxin-antitoxin systems. However, despite the abundant representation in its chromosome, studies have not surveyed the underlying molecular functions in detail, and their biological roles remain enigmatic. In the present study, we found that a chromosomally-encoded MazF family member, predicted at the locus NE1181, is a functional toxin endoribonuclease, and constitutes a toxin-antitoxin system, together with its cognate antitoxin, MazE. Massive parallel se ...[more]