Noninvasive ventilation for severely acidotic patients in respiratory intermediate care units : Precision medicine in intermediate care units.

ABSTRACT:

Background

Severe acidosis can cause noninvasive ventilation (NIV) failure in chronic obstructive pulmonary disease (COPD) patients with acute hypercapnic respiratory failure (AHRF). NIV is therefore contraindicated outside of intensive care units (ICUs) in these patients. Less is known about NIV failure in patients with acute cardiogenic pulmonary edema (ACPE) and obesity hypoventilation syndrome (OHS). Therefore, the objective of the present study was to compare NIV failure rates between patients with severe and non-severe acidosis admitted to a respiratory intermediate care unit (RICU) with AHRF resulting from ACPE, COPD or OHS.

Methods

We prospectively included acidotic patients admitted to seven RICUs, where they were provided NIV as an initial ventilatory support measu

SUBMITTER: Masa JF 

PROVIDER: S-EPMC4937546 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature