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Transcriptome profiling of the rumen epithelium of beef cattle differing in residual feed intake.


ABSTRACT: Feed efficient cattle consume less feed and produce less environmental waste than inefficient cattle. Many factors are known to contribute to differences in feed efficiency, however the underlying molecular mechanisms are largely unknown. Our study aimed to understand how host gene expression in the rumen epithelium contributes to differences in residual feed intake (RFI), a measure of feed efficiency, using a transcriptome profiling based approach.The rumen epithelial transcriptome from highly efficient (low (L-) RFI, n?=?9) and inefficient (high (H-) RFI, n?=?9) Hereford x Angus steers was obtained using RNA-sequencing. There were 122 genes differentially expressed between the rumen epithelial tissues of L- and H- RFI steers (p?

SUBMITTER: Kong RS 

PROVIDER: S-EPMC4979190 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature

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Transcriptome profiling of the rumen epithelium of beef cattle differing in residual feed intake.

Kong Rebecca S G RS   Liang Guanxiang G   Chen Yanhong Y   Stothard Paul P   Guan Le Luo le L  

BMC genomics 20160809


<h4>Background</h4>Feed efficient cattle consume less feed and produce less environmental waste than inefficient cattle. Many factors are known to contribute to differences in feed efficiency, however the underlying molecular mechanisms are largely unknown. Our study aimed to understand how host gene expression in the rumen epithelium contributes to differences in residual feed intake (RFI), a measure of feed efficiency, using a transcriptome profiling based approach.<h4>Results</h4>The rumen ep  ...[more]

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