Development of neurologic diseases in a patient with primate T lymphotropic virus type 1 (PTLV-1).

ABSTRACT:

Background

Virus transmission from various wild and domestic animals contributes to an increased risk of emerging infectious diseases in human populations. HTLV-1 is a human retrovirus associated with acute T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV-1 originated from ancient zoonotic transmission from nonhuman primates, although cases of zoonotic infections continue to occur. Similar to HTLV-1, the simian counterpart, STLV-1, causes chronic infection and leukemia and lymphoma in naturally infected monkeys, and combined are called primate T-lymphotropic viruses (PTLV-1). However, other clinical syndromes typically seen in humans such as a chronic progressive myelopathy have not been observed in nonhuman primates. Little is known abo

SUBMITTER: Enose-Akahata Y 

PROVIDER: S-EPMC4982997 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature