Low frequency of cigarette smoking and the risk of head and neck cancer in the INHANCE consortium pooled analysis.

ABSTRACT:

Background

Cigarette smoking is a major risk factor for head and neck cancer (HNC). To our knowledge, low cigarette smoking (<10 cigarettes per day) has not been extensively investigated in fine categories or among never alcohol drinkers.

Methods

We conducted a pooled analysis of individual participant data from 23 independent case-control studies including 19 660 HNC cases and 25 566 controls. After exclusion of subjects using other tobacco products including cigars, pipes, snuffed or chewed tobacco and straw cigarettes (tobacco product used in Brazil), as well as subjects smoking more than 10 cigarettes per day, 4093 HNC cases and 13 416 controls were included in the analysis. The lifetime average frequency of cigarette consumption was categorized as follows: never cigaret

SUBMITTER: Berthiller J 

PROVIDER: S-EPMC5005938 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature