Clinical associations of immature breathing in preterm infants: part 1-central apnea.

ABSTRACT:

Background

Apnea of prematurity (AOP) is nearly universal among very preterm infants, but neither the apnea burden nor its clinical associations have been systematically studied in a large consecutive cohort.

Methods

We analyzed continuous bedside monitor chest impedance and electrocardiographic waveforms and oxygen saturation data collected on all neonatal intensive care unit (NICU) patients <35 wk gestation from 2009 to 2014 (n = 1,211; >50 infant-years of data). Apneas, with bradycardia and desaturation (ABDs), defined as central apnea ≥10 s associated with both bradycardia <100 bpm and oxygen desaturation <80%, were identified using a validated automated algorithm.

Results

Number and duration of apnea events decreased with increasing gestational age (GA) and postm

SUBMITTER: Fairchild K 

PROVIDER: S-EPMC5015591 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature