High-level viruria as a screening tool for BK virus nephropathy in renal transplant recipients.

ABSTRACT:

Background

Although early monitoring of BK virus infection in renal transplant patients has led to improved outcomes over the past decade, it remains unclear whether monitoring for viremia is the best screening tool for BK virus nephropathy (BKVN).

Methods

We conducted a retrospective review of the medical records of 368 renal transplant recipients who had a minimum of 18 months of posttransplantation follow-up. The relationship between the presence of BK viruria and a composite end point of BK viremia/BKVN was established, and the predictive value of high-grade BK viruria for development of viremia/BKVN was determined.

Results

High grade of BK viruria was present in 110 (30.1%) of the renal transplant recipients. BK viremia/BKVN was present in 64 (17.4%) patients and

SUBMITTER: Chon WJ 

PROVIDER: S-EPMC5025461 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature