Various neurocognitive deficits and conversion risk in individuals at clinical high risk for psychosis.

ABSTRACT:

Aim

Individuals at clinical high risk for psychosis (CHR) exhibit neurocognitive deficits in multiple domains. The aim of this study is to investigate whether several components of neurocognition are predictive of conversion to psychosis.

Methods

Fifty-two CHR individuals were assessed with the Structured Interview for Psychosis Risk Syndromes and completed a battery of neurocognitive tests at baseline including measures of executive functioning, attention, working memory, processing speed and reaction time. Neurocognitive functioning at baseline was scored based on an external normative control group. Most subjects were followed for 2.5 years to determine conversion status.

Results

Significant differences in neurocognitive functioning between CHR individuals and the

SUBMITTER: Mourik K 

PROVIDER: S-EPMC5030118 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature