Economic Outcomes With Anatomical Versus Functional Diagnostic Testing for Coronary Artery Disease.

ABSTRACT:

Background

PROMISE (PROspective Multicenter Imaging Study for Evaluation of Chest Pain) found that initial use of at least 64-slice multidetector computed tomography angiography (CTA) versus functional diagnostic testing strategies did not improve clinical outcomes in stable symptomatic patients with suspected coronary artery disease (CAD) requiring noninvasive testing.

Objective

To conduct an economic analysis for PROMISE (a major secondary aim of the study).

Design

Prospective economic study from the U.S. perspective. Comparisons were made according to the intention-to-treat principle, and CIs were calculated using bootstrap methods. (ClinicalTrials.gov: NCT01174550).

Setting

190 U.S. centers.

Patients

9649 U.S. patients enrolled in PROMISE between Jul

SUBMITTER: Mark DB 

PROVIDER: S-EPMC5046832 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature