Maltodextrin enhances biofilm elimination by electrochemical scaffold.

ABSTRACT: Electrochemical scaffolds (e-scaffolds) continuously generate low concentrations of H₂O₂ suitable for damaging wound biofilms without damaging host tissue. Nevertheless, retarded diffusion combined with H₂O₂ degradation can limit the efficacy of this potentially important clinical tool. H₂O₂ diffusion into biofilms and bacterial cells can be increased by damaging the biofilm structure or by activating membrane transportation channels by exposure to hyperosmotic agents. We hypothesized that e-scaffolds would be more effective against Acinetobacter baumannii and Staphylococcus aureus biofilms in the presence of a hyperosmotic agent. E-scaffolds polarized at -600 mV_Ag/AgCl were overlaid onto preformed biofilms in med

SUBMITTER: Sultana ST 

PROVIDER: S-EPMC5080540 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature