Estrogenic Endocrine Disrupting Chemicals Influencing NRF1 Regulated Gene Networks in the Development of Complex Human Brain Diseases.
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ABSTRACT:
SUBMITTER: Preciados M
PROVIDER: S-EPMC5187886 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
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Estrogenic Endocrine Disrupting Chemicals Influencing NRF1 Regulated Gene Networks in the Development of Complex Human Brain Diseases.
Preciados Mark M Yoo Changwon C Roy Deodutta D
International journal of molecular sciences 20161213 12
During the development of an individual from a single cell to prenatal stages to adolescence to adulthood and through the complete life span, humans are exposed to countless environmental and stochastic factors, including estrogenic endocrine disrupting chemicals. Brain cells and neural circuits are likely to be influenced by estrogenic endocrine disruptors (EEDs) because they strongly dependent on estrogens. In this review, we discuss both environmental, epidemiological, and experimental eviden ...[more]
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