Increased stability of bmr3 mRNA results in a multidrug-resistant phenotype in Bacillus subtilis.

ABSTRACT: A spontaneous mutant isolated in the presence of a high concentration of puromycin acquired a multidrug-resistant phenotype. Expression of the bmr3 gene was dramatically increased. A base substitution, T to A at the +4 position, detected in the mutant resulted in the stabilization of bmr3 mRNA.

SUBMITTER: Ohki R 

PROVIDER: S-EPMC523217 | biostudies-literature | 2004 Nov

REPOSITORIES: biostudies-literature