Optimal detection of infratentorial lesions with a combined dual-echo MRI sequence: "PT2".
Ontology highlight
ABSTRACT: Background
The infratentorial compartment is cardinal for multiple sclerosis (MS) diagnosis. T2-weighted (T2) and proton density-weighted (PD) magnetic resonance imaging (MRI) can visualize infratentorial lesions, but only suboptimally.Objective
To combine PD and T2 for better lesion assessment.Methods
T2 and PD from 35 cases were averaged to form "PT2" images. Two raters counted infratentorial lesions and qualitatively assessed their conspicuity.Results
PT2 showed 244 infratentorial lesions, of which 94% and 74% were seen in PD and T2. PT2 received higher grades for image quality and lesion conspicuity (p < 0.001 for all comparisons).Conclusion
PT2 could improve our ability to diagnose and monitor MS.
SUBMITTER: Gaitan MI
PROVIDER: S-EPMC5267321 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Publications
Optimal detection of infratentorial lesions with a combined dual-echo MRI sequence: "PT2".
Gaitán María I MI Yañes Paulina P Sati Pascal P Romero Carlos C Reich Daniel S DS Correale Jorge J
Multiple sclerosis (Houndmills, Basingstoke, England) 20151109 10
<h4>Background</h4>The infratentorial compartment is cardinal for multiple sclerosis (MS) diagnosis. T2-weighted (T2) and proton density-weighted (PD) magnetic resonance imaging (MRI) can visualize infratentorial lesions, but only suboptimally.<h4>Objective</h4>To combine PD and T2 for better lesion assessment.<h4>Methods</h4>T2 and PD from 35 cases were averaged to form "PT2" images. Two raters counted infratentorial lesions and qualitatively assessed their conspicuity.<h4>Results</h4>PT2 showe ...[more]
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