Dynamic driving pressure associated mortality in acute respiratory distress syndrome with extracorporeal membrane oxygenation.

ABSTRACT:

Background

The survival predictors and optimal mechanical ventilator settings in patients with severe acute respiratory distress syndrome (ARDS) undergoing extracorporeal membrane oxygenation (ECMO) are uncertain. This study was designed to investigate the influences of clinical variables and mechanical ventilation settings on the outcomes for severe ARDS patients receiving ECMO.

Methods

We reviewed severe ARDS patients who received ECMO due to refractory hypoxemia from May 2006 to October 2015. Serial mechanical ventilator settings before and after ECMO and factors associated with survival were analyzed.

Results

A total of 158 severe ARDS patients received ECMO were finally analyzed. Overall intensive care unit (ICU) mortality was 55.1%. After ECMO initiation, tidal

SUBMITTER: Chiu LC 

PROVIDER: S-EPMC5267613 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature