Canalization of C. elegans Vulva Induction against Anatomical Variability.
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ABSTRACT:
SUBMITTER: Huelsz-Prince G
PROVIDER: S-EPMC5330807 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Publications
Canalization of C. elegans Vulva Induction against Anatomical Variability.
Huelsz-Prince Guizela G van Zon Jeroen Sebastiaan JS
Cell systems 20170215 2
It is a fundamental open question as to how embryos develop into complex adult organisms with astounding reproducibility, particularly because cells are inherently variable on the molecular level. During C. elegans vulva induction, the anchor cell induces cell fate in the vulva precursor cells in a distance-dependent manner. Surprisingly, we found that initial anchor cell position was highly variable and caused variability in cell fate induction. However, we observed that vulva induction was "ca ...[more]
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