Metal-free O-H/C-H difunctionalization of phenols by o-hydroxyarylsulfonium salts in water.

ABSTRACT: An environmentally benign method for C-H/O-H difunctionalization of phenols with sulfoxides under mild conditions has been developed. The reaction process is mediated by an electrophilic aromatic substitution and subsequent selective aryl or alkyl migration, involving C-S and C-O bond formations with broad substrate scope.

SUBMITTER: Chen D 

PROVIDER: S-EPMC5361865 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature