Association between polymorphisms in interleukins and oral lichen planus: A meta-analysis.

ABSTRACT:

Background

More and more studies have suggested that single-nucleotide polymorphisms (SNPs) in interleukin (IL) genes are correlated with an increased risk of developing oral lichen planus (OLP). However, these results were inconsistent. Therefore, the aim of this meta-analysis is to retrieve and comprehensively analyze all related clinical studies to investigate the association of ILs gene polymorphisms with the OLP risk.

Methods

PubMed, Embase, and the Cochrane Library were searched for eligible studies to evaluate the association between IL polymorphisms and the OLP. The odds ratios (ORs) and 95% confidence intervals (CIs) from each study were pooled to estimate the strength of the association. Statistical analyses were performed by using STATA software.

Results

In

SUBMITTER: Shi Q 

PROVIDER: S-EPMC5369898 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature