The role of scheduled second TACE in early-stage hepatocellular carcinoma with complete response to initial TACE.

ABSTRACT:

Background/aims

We investigated the outcomes of early-stage hepatocellular carcinoma (HCC) patients who showed a complete response (CR) to initial transarterial chemoembolization (TACE), with a focus on the role of scheduled TACE repetition.

Methods

A total of 178 patients with early-stage HCC who were initially treated with TACE and showed a CR based on the modified Response Evaluation Criteria in Solid Tumors (mRECIST) criteria on one month follow-up computed tomography (CT) were analyzed. Among them, 90 patients underwent scheduled repetition of TACE in the absence of viable tumor on CT.

Results

During a median follow-up period of 4.6 years (range: 0.4-8.8 years), mortality was observed in 71 patients (39.9%). The overall recurrence-free and local recurrence-free s

SUBMITTER: Kim JH 

PROVIDER: S-EPMC5381828 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature