Renal dysplasia characterized by prominent cartilaginous metaplasia lesions in VACTERL association: A case report.

ABSTRACT:

Background

Renal dysplasia is the most important cause of end-stage renal disease in children. The histopathological characteristic of dysplasia is primitive tubules with fibromuscular disorganization. Renal dysplasia often includes metaplastic cartilage. Metaplastic cartilage in renal dysplasia has been explained as occurring secondary to vesicoureteral reflux (VUR). Additionally, renal dysplasia is observed in renal dysplasia-associated syndromes, which are combinations of multiple developmental malformations and include VACTERL association.

Case presentation

We observed the following multiple developmental malformations in a 108-day-old male infant during a nephrectomy: a nonfunctioning right kidney with VUR, hemidiaphragmatic eventration, a ventricular septal defect (VSD

SUBMITTER: Nakaya T 

PROVIDER: S-EPMC5403075 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature