Pneumonia after cardiac surgery: Experience of the National Institutes of Health/Canadian Institutes of Health Research Cardiothoracic Surgical Trials Network.

ABSTRACT:

Rationale

Pneumonia remains the most common major infection after cardiac surgery despite numerous preventive measures.

Objectives

To prospectively examine the timing, pathogens, and risk factors, including modifiable management practices, for postoperative pneumonia and estimate its impact on clinical outcomes.

Methods

A total of 5158 adult cardiac surgery patients were enrolled prospectively in a cohort study across 10 centers. All infections were adjudicated by an independent committee. Competing risk models were used to assess the association of patient characteristics and management practices with pneumonia within 65 days of surgery. Mortality was assessed by Cox proportional hazards model and length of stay by a multistate model.

Measurements and main results

SUBMITTER: Ailawadi G 

PROVIDER: S-EPMC5439299 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature