Functional male accessory glands and fertility in Drosophila require novel ecdysone receptor.
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ABSTRACT: In many insects, the accessory gland, a secretory tissue of the male reproductive system, is essential for male fertility. Male accessory gland is the major source of proteinaceous secretions, collectively called as seminal proteins (or accessory gland proteins), which upon transfer, manipulate the physiology and behavior of mated females. Insect hormones such as ecdysteroids and juvenoids play a key role in accessory gland development and protein synthesis but little is known about underlying molecular players and their mechanism of action. Therefore, in the present study, we examined the roles of hormone-dependent transcription factors (Nuclear Receptors), in accessory gland development, function and male fertility of a genetically tractable insect model, Drosophila melanogaster. First,
SUBMITTER: Sharma V
PROVIDER: S-EPMC5444863 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
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