Patterns of Oxygenation, Mortality, and Growth Status in the Surfactant Positive Pressure and Oxygen Trial Cohort.

ABSTRACT:

Objective

To characterize actual achieved patterns of oxygenation in infants born appropriate vs small for gestational age (SGA) randomized to a lower (85-89%) vs higher (91%-95%) oxygen saturation target in the Surfactant Positive Pressure and Oxygen Trial. To determine the association between achieved oxygen saturation levels and survival in infants born appropriate vs SGA enrolled in the Surfactant Positive Pressure and Oxygen Trial.

Study design

Median oxygen saturation and intermittent hypoxemia events (<80%, 20 seconds-5  minutes) were documented in 1054 infants of 24^0/7-27^6/7 weeks of gestation while receiving supplemental oxygen during the first 3 days of life.

Results

Lower target infants who were small for gestational age had the lowest

SUBMITTER: Di Fiore JM 

PROVIDER: S-EPMC5484739 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature