Relationship of Topology, Multiscale Phase Synchronization, and State Transitions in Human Brain Networks.

ABSTRACT: How the brain reconstitutes consciousness and cognition after a major perturbation like general anesthesia is an important question with significant neuroscientific and clinical implications. Recent empirical studies in animals and humans suggest that the recovery of consciousness after anesthesia is not random but ordered. Emergence patterns have been classified as progressive and abrupt transitions from anesthesia to consciousness, with associated differences in duration and electroencephalogram (EEG) properties. We hypothesized that the progressive and abrupt emergence patterns from the unconscious state are associated with, respectively, continuous and discontinuous synchronization transitions in functional brain networks. The discontinuous transition is explainable with the concept of

SUBMITTER: Kim M 

PROVIDER: S-EPMC5492767 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature