Optical See-Through Cancer Vision Goggles Enable Direct Patient Visualization and Real-Time Fluorescence-Guided Oncologic Surgery.

ABSTRACT:

Background

The inability to visualize the patient and surgical site directly, limits the use of current near infrared fluorescence-guided surgery systems for real-time sentinel lymph node biopsy and tumor margin assessment.

Methods

We evaluated an optical see-through goggle augmented imaging and navigation system (GAINS) for near-infrared, fluorescence-guided surgery. Tumor-bearing mice injected with a near infrared cancer-targeting agent underwent fluorescence-guided, tumor resection. Female Yorkshire pigs received hind leg intradermal indocyanine green injection and underwent fluorescence-guided, popliteal lymph node resection. Four breast cancer patients received ^99mTc-sulfur colloid and indocyanine green retroareolarly before undergoing sentinel lymph node bio

SUBMITTER: Mondal SB 

PROVIDER: S-EPMC5503161 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature