A unified multi-level model approach to assessing patient responsiveness including; return to normal, minimally important differences and minimal clinically important improvement for patient reported outcome measures.

ABSTRACT:

Objective

This article reviews and compares four commonly used approaches to assess patient responsiveness with a treatment or therapy (return to normal (RTN), minimal important difference (MID), minimal clinically important improvement (MCII), OMERACT-OARSI [Outcome Measures in Rheumatology-Osteoarthris Reseach Society International] (OO)) and demonstrates how each of the methods can be formulated in a multilevel modelling (MLM) framework.

Design

Cohort study.

Setting

A cohort of patients undergoing total hip and knee replacement were recruited from a single UK National Health Service hospital.

Population

400 patients from the Arthroplasty Pain Experience cohort study undergoing total hip (n=210) and knee (n=190) replacement who completed the Intermittent and

SUBMITTER: Sayers A 

PROVIDER: S-EPMC5577889 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature