A Systematic Review of Metastatic Hepatocellular Carcinoma to the Spine.

ABSTRACT:

Background

Hepatocellular carcinoma (HCC) frequently metastasizes to the spine. The impact of medical and/or surgical intervention on overall survival has been examined in a limited number of clinical studies, and herein we systematically review these data.

Methods

We performed a literature review using PubMed, Embase, CINAHL, and Web of Science to identify articles that reported survival, clinical outcomes, and/or prognostic factors associated with patients diagnosed with spinal metastases. The methodologic quality of each review was assessed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses tool.

Results

There were 26 articles (152 patients) that met the inclusion criteria and were treated with either surgery, radiotherapy, chemotherapy, a

SUBMITTER: Goodwin CR 

PROVIDER: S-EPMC5586495 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature