Serum levels of adiponectin and leptin as biomarkers of proteinuria in lupus nephritis.

ABSTRACT:

Introduction

There are controversial results about the role of serum leptin and adiponectin levels as biomarkers of the severity of proteinuria in lupus nephritis.

Objective

The aim of this study was to evaluate the relationship between serum leptin and adiponectin levels with severity of proteinuria secondary to lupus nephritis (LN).

Methods

In a cross-sectional study, 103 women with systemic lupus erythematosus (SLE) were evaluated for kidney involvement. We compared 30 SLE patients with LN, all of them with proteinuria, versus 73 SLE patients without renal involvement (no LN). A comprehensive set of clinical and laboratory variables was assessed, including serum levels of leptin and adiponectin by ELISA. Multivariate analyses were used to adjust for potential confo

SUBMITTER: Diaz-Rizo V 

PROVIDER: S-EPMC5595281 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature