Impact of Timing on the Functional Recovery Achieved With Platelet Supplementation After Treatment With Ticagrelor.

ABSTRACT:

Background

American College of Cardiology/American Heart Association guidelines advise waiting 5 to 7 days before operating on P2Y₁₂ inhibitor-treated acute coronary syndrome patients, to allow dissipation of its antiplatelet effects. Platelet transfusion is often used to restore hemostasis during operations, but its effectiveness and optimal timing are unclear. We investigated the degree of functional gains obtained from platelet supplementation after loading and maintenance of dual antiplatelet therapy with ticagrelor and the influence of timing on this strategy.

Methods and results

After baseline platelet testing (Multiplate Analyzer and VerifyNow), cardiovascular disease patients (n=20; 56.9±7.9 years; 65% men; 75% diabetic) received dual antiplatelet therapy

SUBMITTER: Zafar MU 

PROVIDER: S-EPMC5656402 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature