Selective Screening Strategies for Gestational Diabetes: A Prospective Cohort Observational Study.

ABSTRACT:

Aim

We aimed to develop a prediction model for the diagnosis of gestational diabetes and to evaluate the performance of published prediction tools on our population.

Methods

We conducted a cohort study on nondiabetic women < 26 weeks gestation at a level 1 clinic in Johannesburg, South Africa. At recruitment, participants completed a questionnaire and random basal glucose and HbA1c were evaluated. A 75 g 2-hour OGTT was scheduled between 24-28 weeks gestation, as per FIGO guidelines. A score was derived using multivariate logistic regression. Published scoring systems were tested by deriving ROC curves.

Results

In 554 women, RBG, BMI, and previous baby ≥ 4000 g were significant risk factors included for GDM, which were used to derive a nomogram-based score. The logist

SUBMITTER: Adam S 

PROVIDER: S-EPMC5671730 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature