Risk of cardiovascular disease among women with endometrial cancer compared to cancer-free women in the Women's Health Initiative.

ABSTRACT:

Background

The majority of women diagnosed with endometrial cancer (EC) have low cancer-specific mortality; however, a high prevalence of cardiovascular disease (CVD) risk factors places EC patients at high risk of developing CVD. In the Women's Health Initiative (WHI), we assessed the hypothesis that CVD risk was higher among women who developed EC compared with women who did not develop EC.

Methods

We compared the incidence of fatal and non-fatal CVD events among 1,179 women who developed Type I EC, 211 women who developed Type II EC, and 92,217 women who did not develop EC. We first estimated univariable cause-specific hazard ratios (CHRs) and 95% confidence intervals (CIs) for the association between an EC diagnosis (overall and by EC type) with CVD risk using Cox propor

SUBMITTER: Felix AS 

PROVIDER: S-EPMC5700837 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature