Pregnancy-specific stress, fetoplacental haemodynamics, and neonatal outcomes in women with small for gestational age pregnancies: a secondary analysis of the multicentre Prospective Observational Trial to Optimise Paediatric Health in Intrauterine Growth Restriction.

ABSTRACT:

Objectives

To examine associations between maternal pregnancy-specific stress and umbilical (UA PI) and middle cerebral artery pulsatility indices (MCA PI), cerebroplacental ratio, absent end diastolic flow (AEDF), birthweight, prematurity, neonatal intensive care unit admission and adverse obstetric outcomes in women with small for gestational age pregnancies. It was hypothesised that maternal pregnancy-specific stress would be associated with fetoplacental haemodynamics and neonatal outcomes.

Design

This is a secondary analysis of data collected for a large-scale prospective observational study.

Setting

This study was conducted in the seven major obstetric hospitals in Ireland and Northern Ireland.

Participants

Participants included 331 women who participated

SUBMITTER: Levine TA 

PROVIDER: S-EPMC5734406 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature