Phylodynamic and Genetic Diversity of Canine Parvovirus Type 2c in Taiwan.

ABSTRACT: Canine parvovirus type 2c (CPV-2c) emerged in 2000 and is known for causing a more severe disease than other CPV-2 variants in puppies. In 2015, the emerging CPV-2c variant was isolated in Taiwan and it subsequently became the predominant variant. To trace the evolution of Taiwanese CPV-2c, we compared complete VP2 genes of CPV-2c from Taiwan and sequences obtained from GenBank. The evolutionary rate of CPV-2c was estimated to be 4.586 × 10^-4 substitutions per site per year (95% highest posterior density (HPD) was 3.284-6.076 × 10^-4). The time to the most recent common ancestor (TMRCA) dated to 1990 (95% HPD: 1984-1996) and 2011 (95% HPD: 2010-2013) for the CPV-2c variant and Taiwanese isolates, respectively. The CPV-2c variant isolated from Taiwan was clustered with

SUBMITTER: Lin YC 

PROVIDER: S-EPMC5751304 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature