Nanostructured titanium surfaces exhibit recalcitrance towards Staphylococcus epidermidis biofilm formation.

ABSTRACT: Titanium-based implants are ubiquitous in the healthcare industries and often suffer from bacterial attachment which results in infections. An innovative method of reducing bacterial growth is to employ nanostructures on implant materials that cause contact-dependent cell death by mechanical rupture of bacterial cell membranes. To achieve this, we synthesized nanostructures with different architectures on titanium surfaces using hydrothermal treatment processes and then examined the growth of Staphylococcus epidermidis on these surfaces. The structure obtained after a two-hour hydrothermal treatment (referred to as spear-type) showed the least bacterial attachment at short times but over a period of 6 days tended to support the formation of thick biofilms. By contrast, the structure obtain

SUBMITTER: Cao Y 

PROVIDER: S-EPMC5773551 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature