Ontology highlight
ABSTRACT:
SUBMITTER: Freytag V
PROVIDER: S-EPMC5802460 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Translational psychiatry 20180131 1
The large biological distance between genetic risk loci and their mechanistic consequences in the tissue of interest limits the ability to establish functionality of susceptibility variants for genetically complex traits. Such a biological gap may be reduced through the systematic study of molecular mediators of genomic action, such as epigenetic modification. Here, we report the identification of robust genetic estimators of whole-blood CpG methylation, which can serve as intermediate molecular ...[more]