Topical Osmoprotectant for the Management of Postrefractive Surgery-Induced Dry Eye Symptoms: A Randomised Controlled Double-Blind Trial.

ABSTRACT:

Background

Dry eye disease (DED) is one of the most common complications following refractive surgery.

Purpose

Evaluate the efficacy of an osmoprotective eye drop (Optive®) for the management of induced DED in refractive surgery patients.

Design

Double-masked randomised controlled trial.

Methods

Twenty-two refractive surgery patients oriented to apply FreshTears (FT; n = 13) or Optive (Op; n = 9), topically, QID, for 3 months. Eye exams were performed before surgery (T0) and 1-month (T1) and 3-month (T3) follow-up and consisted of tear film osmolarity, Schirmer 1 test, tear film breakup time (TBUT), fluorescein staining, and ocular surface disease index (OSDI) and patient symptoms questionnaires.

Main outcome measures

Pain and osmolarity.

SUBMITTER: Hazarbassanov RM 

PROVIDER: S-EPMC5838485 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature