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WIsH: who is the host? Predicting prokaryotic hosts from metagenomic phage contigs.

ABSTRACT:

Summary

WIsH predicts prokaryotic hosts of phages from their genomic sequences. It achieves 63% mean accuracy when predicting the host genus among 20 genera for 3 kbp-long phage contigs. Over the best current tool, WisH shows much improved accuracy on phage sequences of a few kbp length and runs hundreds of times faster, making it suited for metagenomics studies.

Availability and implementation

OpenMP-parallelized GPL-licensed C ++ code available at https://github.com/soedinglab/wish.

Contact

clovis.galiez@mpibpc.mpg.de or soeding@mpibpc.mpg.de.

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Galiez C

PROVIDER: S-EPMC5870724 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature

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WIsH: who is the host? Predicting prokaryotic hosts from metagenomic phage contigs.

Galiez Clovis C Siebert Matthias M Enault François F Vincent Jonathan J Söding Johannes J

Bioinformatics (Oxford, England) 20171001 19

<h4>Summary</h4>WIsH predicts prokaryotic hosts of phages from their genomic sequences. It achieves 63% mean accuracy when predicting the host genus among 20 genera for 3 kbp-long phage contigs. Over the best current tool, WisH shows much improved accuracy on phage sequences of a few kbp length and runs hundreds of times faster, making it suited for metagenomics studies.<h4>Availability and implementation</h4>OpenMP-parallelized GPL-licensed C ++ code available at https://github.com/soedinglab/w ...[more]

PMID: 28957499

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