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Pathologic and molecular characterization of Streptococcus dysgalactiae subsp. equisimilis infection in neonatal piglets.


ABSTRACT: Streptococcus dysgalactiae subspecies equisimilis (SDSE) is an emerging pathogen in animals and humans. Herein, we describe two clinical swine cases of SDSE infection presenting with lameness, neurological signs, or sudden death. Pathological examination indicated suppurative arthritis, encephalitis, and multifocal abscesses in kidney and heart. The ?-hemolytic colonies obtained from joint samples of each case were identified as SDSE. The two isolates had low minimum inhibitory concentrations for ?-lactams, and they presented the same virulence gene profile (slo-/sagA?/pSTKP8?). Molecular analysis by multilocus sequence typing identified the SDSE isolates from cases 1 and 2 as sequence types 315 and 252, respectively.

SUBMITTER: Oh SI 

PROVIDER: S-EPMC5879081 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature

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Pathologic and molecular characterization of <i>Streptococcus dysgalactiae</i> subsp. <i>equisimilis</i> infection in neonatal piglets.

Oh Sang-Ik SI   Kim Jong Wan JW   Jung Ji-Youl JY   Chae Myeongju M   Lee Yu-Ran YR   Kim Jong Ho JH   So ByungJae B   Kim Ha-Young HY  

Journal of veterinary science 20180301 2


<i>Streptococcus dysgalactiae</i> subspecies <i>equisimilis</i> (SDSE) is an emerging pathogen in animals and humans. Herein, we describe two clinical swine cases of SDSE infection presenting with lameness, neurological signs, or sudden death. Pathological examination indicated suppurative arthritis, encephalitis, and multifocal abscesses in kidney and heart. The β-hemolytic colonies obtained from joint samples of each case were identified as SDSE. The two isolates had low minimum inhibitory con  ...[more]

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